Primary drug resistance persists in recently HIV-1 infected adults.

2004 NOV 11 - (NewsRx.com & NewsRx.net) -- Primary drug resistance persists in recently HIV-1 infected adults.

"Primary, or transmitted, drug resistance is common among treatment naive patients recently infected with HIV-1, and impairs response to anti-retroviral therapy," wrote investigators in the United States.

"We previously observed that patients with secondary resistance (developed in response to anti-retroviral treatment) who chose to stop an anti-retroviral regimen experience rapid overgrowth of drug resistant viruses by wild-type virus of higher pol replication capacity.

"We sought to determine if primary drug resistance would be lost at a …